Improving the Safety and Security of Biological Research

Executive Order 2025-08266
Signed on May 6, 2025
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What it means

Restricts federally funded "gain-of-function" biological research, particularly in countries like China. It orders immediate suspension of dangerous research funding overseas and directs development of stronger oversight frameworks for all biological research within 120 days.

Expected impact

  • Enhanced biosecurity through stricter oversight of potentially dangerous pathogen research
  • Limitation of American-funded biological research in countries deemed to have insufficient safety controls
  • Possible slowdown in certain biological research areas while new frameworks are established
  • New reporting requirements for research institutions, increasing transparency around potentially dangerous research
  • Creation of enforcement mechanisms including funding revocation and up to 5-year ineligibility periods for violators
  • Potential tension with foreign research partners, particularly China

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